I'm sorry this is going so poorly for you.
If you're still willing to give it a shot, I recommend this, since a newer, more stable patch is due out today (1.0.2)
1. Uninstall the game
2. Delete the entire directory structure (you can save your saved games, if you have any)
3. Get a full copy of the new patched version, when it is released.
4. Install 1.0.2, and come pester us some more if it's still not working.
We'd really like to help you enjoy this game!
Steve