Ok first off, uninstall one more time.... Because the game actually uses 3 file locations in Vista.
Besides the two you mention here
Quote:
C:\Program Files\Sports Interactive\OOTP Baseball 2007
or the one here:
C:\Users\myname\Documents\Sports Interactive\OOTP Baseball 2007
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There is also a Hidden Folder.....
So first step is to enable seeing hidden folders, then Goto Admin in the start menu (Could possibly be your User ID name, I never named mine) Top right side of the Start menu, then you should see App Data. Make sure everything is deleted there.
Then Re install the game and the first time you load the game, right click and choose run as Admin.
If this doesn't work I will check back in a bit