[towerbooks3192]

I am a total noob of the game and I still have trouble with it. Here is what I did to kinda get in to a game and see some results

1) Read the manual and work your way around the UI and familiarise where things are.
2) Once you kind of know how to work around the UI, read about topics such as how to set-up your line-up, how to choose good players and what decisions to use if you decide to call the shots in a game.
3) Read some intro to sabermetrics and other articles that relate to using stats in making decisions.
4) Find a playstyle you want (e.g buy players and never worry about setting line-ups, focus on setting line-ups or micromanage everything).
5) Play on and ask questions here as you go.
6) The knowledge page on the wiki points out to some good threads here that really skyrocket my knowledge relating to the game from knowing totally nothing.

Just play and continue and ask as you go. Also don't be scared of losing and it is important to learn from it and see where you went wrong and apply it to your next game. Never let the fear of striking out keep you from playing the game.

edit: I missed the part you are new to baseball. I am also new to baseball but I managed to learn and appreciate the sport even more. My advice is looking at a youtube video that explains the basic of the sport. There was a cool video that explained the sport and used some cool whiteboard drawings. Next thing you want to know is what those things on the box score mean, knowing how to read the box scores and game logs really helps a lot. Wikipedia and other sources or even the in-game glossary can help a lot with some elements of the box score.