[Bluenoser]

High # - more likely to be talent changes - eg: Top prospects turn out to be duds, there's more Mike Piazza types

Low # - less likely to be talent changes - eg: Top prospects/picks will be more likely to remain top prospects/players, less Piazza types (late picks coming out of no where to be all stars)

Normal talent changes will still occur of course - as a guy gets older, he'll slowly lose his talent. (there are settings to control how fast/slow that happens also)

Myself I play fictional and mostly I don't care for a lot of talent changes so I use 50. It's a personal choice thing though.