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Yes, generally speaking everything will apply to games in progress except for roster updates.
There may always be some slight things that would be better to wait for - for example, AI actions may change slightly, so sometimes you may get a little more roster turnover after applying a patch if the AI changes its mind with patch changes. But generally speaking, those aren't usually very large, and there weren't any massive algorithmic changes that should cause issues in this upcoming patch, specifically.
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