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This is what I do when I play my simulation before the end of the 1871 season, I play with real trade and, since there is no trade database loaded before January first 1872, the AI teams will start signing players who aren't suppose to play the following season or are unassigned rookie (because of the league structure in OOTP but this is another story). Only problem with this if you forgot to uncheck it is that the AI teams will do no moves at all... not only trade and free agent, but they won't replace an injured player or change the starting lineup from game to game or make move between them and their reserve rooster.
I only use that for one reason and it's to stay historically accurate so I have no idea if what I said is also true in a fictional context...
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